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Click here for the index of all years
December 2025
November 2025
October 2025
September 2025
- In 2019 Thomas Carmichael at UCLA discovered that the CCR5 gene is associated with stroke recovery and that the drug Maraviroc boosts neuroplasticity after brain injury for example after a stroke (Stroke is the leading cause of adult disability). CCR5 is a therapeutic target for recovery after stroke and traumatic brain injury.
(paper)
(The CCR5 receptor is also the portal that HIV binds to in order to enter cells).
His team have now identified a potential "brain rehabilitation" drug.
(paper)
August 2025
July 2025
June 2025
May 2025
- James Monaghan's team at Northeastern University discovered that a chemical called retinoic acid (a form of vitamin A) is involved in the axolotl salamander's ability to regenerate its limbs after they are severed. Different concentrations of retinoic acid are different signals for the growth of limbs. The key protein that regulates the concentration of retinoic acid is CYP26b1. Retinoic acid is also secreted by humans and the genes involved in axolotl's limb regeneration are also present in human DNA, but somehow these genes don't get expressed in human adults. (paper)
April 2025
March 2025
- Yifat Merbl's team at the Weizmann Institute of Science in Israel has discovered that a new part of the immune system the proteasome, a structure present in every cell of the body whose normal function is to recycles proteins, becomes a produceer of antibiotics when it detects that the cell has been infected by bacteria. De facto, this is an immune system that spreads throughout the body in all the cells that can generate a new class of antibiotics. (paper).
February 2025
- Gawon Cho at Yale has shown that deep sleep and REM sleep are important for brain health and dementia risk. Lower slow wave sleep and lower REM sleep are associated with brain atrophy. Those brains show signs of atrophy in MRI scans 13 to 17 years later.
(paper)
January 2025
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